Because of the relatively benign nature of non-melanoma skin cancers, non-surgical treatment options have been developed over the last few decades.
Non-surgical treatments include cryotherapy, topical fluorouracil and imiquimod creams, as well as photodynamic therapy with methyl aminolevulinate hydrochloride.
Radiotherapy also provides an excellent alternative in many cases of non-melanoma skin cancer, particularly when surgery is relatively contraindicated. It is also useful as an adjunctive therapy to surgery in difficult or recurrent cases of skin cancer.